Hif1a promoter
Web614528 - HIF1A ANTISENSE RNA 1; HIF1AAS1 - ANTISENSE HIF1-ALPHA, 5-PRIME;; AHIF1A, 5-PRIME ... DNA topoisomerase I inhibition by camptothecin induces escape of RNA polymerases II from promoter-proximal pause site, antisense transcription and histone acetylation at the human HIF-1-alpha gene locus. Nucleic Acids Res. 38: ... Web2 de ago. de 1999 · Hypoxia inducible factor-1 (HIF-1) is a transcription factor composed of two subunits, HIF-1α and ARNT, which is activated under hypoxia. HIF-1α mRNA is …
Hif1a promoter
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WebMITF binds to the Hif1a promoter and induces Hif1α gene expression. (A) Schematic representation of the Hif1a promoter. Black arrow denotes the ubiquitously expressed … Web8 de fev. de 2013 · The ubiquitously expressed hypoxia-inducible factor-1α (HIF-1α) acts as a key transcription factor in regulating metabolism, development, cellular survival, …
Webthat the tumor promoter and tumor suppressor activity of HIF1 a is cell-type- and compartment-specific, and may be due to its ability to functionally induce autophagy. In accordance with this idea, both fibroblasts and breast cancer cells expressing activated HIF1a showed the characteristic induction of autophagosomes, Web1 de mar. de 2006 · The proliferation of Hif1a −/− embryonic stem cells may be impaired when cultured under hypoxic conditions for 24–48 hr (Carmeliet et al., 1998, Iyer et al., 1998).The proliferation of Hif1a −/− MEFs was also impaired after 48 hr of hypoxia (Figure 1 E) as was previously observed (Seagroves et al., 2001).However, a more striking defect …
WebHIF1A gene expression downstream of ALK signaling is stimulated by binding of phosphorylated STAT3 to the promoter. HIF1A expression contributes to cell growth by supporting angiogenesis and survival under hypoxic conditions (Marzek et al, 2011; Martinengo et al, 20014; reviewed in Werner et al, 2024). Web1 de dez. de 2024 · The core of the putative promoter region was characterized in terms of transcription factors responsive elements both by bioinformatic studies and promoter …
Web11 linhas · pGL2B-HIF1A prom: HIF1A promoter fragment (Homo sapiens) Minella Add …
Web6 de ago. de 2024 · Moreover, deletion of the MYC binding element in the HIF1A reporter construct greatly diminished the promoter activity of HIF1A compared with the wild-type HIF1A reporter construct (Fig. 3f). Taken together, these results demonstrate that MYC activates HIF1A transcription by directly binding to a consensus E-box sequence at − … flps and life insuranceWeb11 de abr. de 2024 · HIF1A-As2 recruits DHX9 on MYC promoter and activates MYC. expression. LncRNAs can modulate genes in trans or in cis [30]. In our study, we observed that the depletion of HIF1A-As2 with two different. flp s.a.r.lWeb5 de jul. de 2024 · We functionally characterized two hypoxia responsive elements within the proximal promoter of CSRP2 gene which are targeted by hypoxia-inducible factor-1 … greendale lions foundationWeb22 de abr. de 2024 · With the interest to know if DNA methylation was associated with the modulation of Vegfa and Hif1a expression in AKI to CKD transition, we assessed the … greendale liquor worcesterWeb21 de mar. de 2024 · Complete information for HIF1A gene (Protein Coding), Hypoxia Inducible Factor 1 Subunit Alpha, including: function, proteins, disorders, pathways ... flp scoutWeb2 de jun. de 2024 · To confirm the results from bioinformatics analysis, we detected HIF-1α expression and HIF1A promoter interaction with c-Myc by quantitative real-time PCR and ChIP, respectively, after regulating the expression of WDR5 and c-Myc. HIF-1α expression was extensively reduced when WDR5 was knocked down, and it increased when Myc … greendale lions family 4th festWeb1 de ago. de 2008 · The HIF1A promoter activity was significantly increased in ionomycin-activated mast cells, and the promoter activity could be inhibited by CsA and FK506. … greendale library hours today